COVID-19, obesity, and immune response 2 years after the pandemic: A timeline of scientific advancesArticle Published on 2022-10-012022-11-16 Journal: Obesity Reviews [Category] COVID19(2023년), SARS, 변종, [키워드] Adiposity body mass index C-reactive protein COVID-19 COVID-19 pandemic described explain expressed immune immune dysregulation immune response individual Inflammatory inflammatory markers inquiry mechanism obesity pathophysiology patients patients with obesity pharmacological treatments poor prognosis progressed researcher SARS-CoV-2 Science scientific advances. the disease vaccination variants [DOI] 10.1111/obr.13496 PMC 바로가기
SARS-CoV-2 infects adipose tissue in a fat depot- and viral lineage-dependent mannerArticle Published on 2022-09-292022-11-15 Journal: Nature Communications [Category] SARS, 변종, 진단, [키워드] ACE2 adipose Adiposity anatomical Cell cell death cells cellular response Disease progression Express expression fat fat cell infect Infection Lineage occur pro-inflammatory cytokines risk factor SARS-CoV-2 SARS-COV-2 infection severe COVID-19 susceptibility susceptible the SARS-CoV-2 tissue variant viability visceral [DOI] 10.1038/s41467-022-33218-8 PMC 바로가기
The impact of body composition on mortality of COVID-19 hospitalized patients: A prospective study on abdominal fat, obesity paradox and sarcopeniaResearch article Published on 2022-07-012022-10-05 Journal: Clinical nutrition ESPEN [Category] COVID19(2023년), SARS, 바이오마커, [키워드] absence adipose Adiposity Admission age Analysis Bioimpedance analysis BMI body composition clinic Clinical outcome Comorbidity Complication conducted COVID-19 COVID-19 patient described diagnosis of SARS-CoV-2 distribution enrolled Factor fat five group five groups form hospital Hospitalized hypertension ICU ICU admission immune Infection Infectious disease Inflammatory Inflammatory marker intensity intensive care IQR Italy Laboratory male Mortality non-infectious obesity obesity paradox outcome Patient Predictive prospective observational study Prospective Study Result risk factor sarcopenia SARS-CoV-2 significant difference significantly study population submitted Support syndrome tissue ventilator ventilatory ventilatory support visceral Waist circumference with COVID-19 women [DOI] 10.1016/j.clnesp.2022.07.003 [Article Type] Research article
Association of epicardial adipose tissue with the severity and adverse clinical outcomes of COVID-19: A meta-analysisReview article Published on 2022-07-012022-10-05 Journal: International Journal of Infectious Diseases [Category] 바이오마커, 임상, [키워드] 95% confidence interval adipose Adiposity Adverse adverse outcome chronic obstructive CIs Clinical outcome Computed tomography Control Coronary artery disease COVID-19 COVID-19 severity database diabetes Effect Epicardial adipose tissue help Hospitalization independent intensive care Invasive mechanical ventilation mean difference measure Meta-analysis objective Patient patients with COVID-19 poor prognosis positive primary end point Prognosis prognostic risk stratification pulmonary disease Quantitative Result risk factor Risk factors searched severe group severity SMD tissue visceral [DOI] 10.1016/j.ijid.2022.04.013 [Article Type] Review article
The association between micronutrients and the SARS-CoV-2-specific antibodies in convalescent patients회복기 환자에서 미량 영양소와 SARS-CoV-2 특이 항체 사이의 연관성Original Paper Published on 2022-02-212022-09-10 Journal: Infection [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Adiposity antibodies antibody antibody synthesis association biochemical changes in Clinical features Concentration convalescent COVID-19 patient convalescent patient correlated correlation COVID-19 infection evaluate evaluated female female participants greater Healthcare workers hematological parameters Humoral immunity IgG IgG antibodies IgM IgM and IgG immune response immune responses immune system Infection LDH male participant male participants Micronutrient micronutrients Pandemics Platelet positive correlation positively correlated recovered patient recovered patients required Result robustness SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2-specific antibody SARS-CoV-2-specific IgG serum significant negative correlation specific IgM subject susceptibility susceptibility to infection Validity Viral viral infection Vitamin Vitamin D Zinc [DOI] 10.1007/s15010-022-01774-2 PMC 바로가기 [Article Type] Original Paper
COVID-19–Related Life Experiences, Outdoor Play, and Long-term Adiposity Changes Among Preschool- and School-Aged Children in Singapore 1 Year After Lockdown코로나19 관련 생활 경험, 야외 놀이, 폐쇄 1년 후 싱가포르 미취학 아동 및 취학 연령 아동의 장기 비만 변화Research Published on 2022-01-242022-09-12 Journal: JAMA Pediatrics [Category] MERS, SARS, 진단, [키워드] 95% CI activities Adiposity adjusted odds ratio age assessment association body mass body mass index calculated change changes changes in Child children clinical implication Cohort cohort study cohorts COVID-19 COVID-19 infection COVID-19–related lockdown difference effort eligible eliminated Elimination event exposure finding Future Importance increase in introduced life Linear regression lockdown lockdowns Lower Maternal measure mitigate objective outcome parent participant Participants Point Preschool prevalent proportion Relevance reported Research Result setting Singapore Singapore dollar Year [DOI] 10.1001/jamapediatrics.2021.5585 PMC 바로가기 [Article Type] Research
Associations between body composition, fat distribution and metabolic consequences of excess adiposity with severe COVID-19 outcomes: observational study and Mendelian randomisation analysisObservational Study Published on 2022-01-142022-10-04 Journal: International journal of obesity (2005) [Category] MERS, 바이오마커, 유전자 메커니즘, 임상, [키워드] Adiposity adjusted Admission Analysis association BMI body composition body mass index COVID-19 death diabete Evidence examined excess fat fat distribution genetics Hospital admission ICU incidence increased risk initiative intensive care metabolic consequence Microbiology MR analyses MR analysis muscle mass outcome Participants pathway prospective cohort study randomisation remained Result severe COVID-19 severity of COVID-19 suggested Support Type type 2 diabetes UK biobank with COVID-19 [DOI] 10.1038/s41366-021-01054-3 PMC 바로가기 [Article Type] Observational Study
Paternally expressed gene 3 ( Pw1/Peg3 ) promotes sexual dimorphism in metabolism and behavior친밀하게 발현 된 유전자 3 (PW1/PEG3)은 신진 대사와 행동에서 성 이형성을 촉진합니다Research Article Published on 2022-01-132022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] accelerated Adiposity adulthood age allele alteration Behavior Brain Cell cells Characteristics consequence contribute develop Diabetic Endocrine Epigenetic examined expressed expressing fat accumulation Fatty liver female genomic genomic imprinting gonadal growth hormone insulin insulin resistance life loss of function male mammal mammals manifested masculinization metabolism mice mutant observation parental pathway Peg3 phenotypic postnatal development proliferative promote provide puberty question reduced Regulation selective Sex sex steroid sexual dimorphism Signaling steroid Support tissues weaning [DOI] 10.1371/journal.pgen.1010003 PMC 바로가기 [Article Type] Research Article
Metabolic health, menopause, and physical activity—a 4-year follow-up studyArticle Published on 2021-11-202022-10-04 Journal: International journal of obesity (2005) [Category] 바이오마커, [키워드] 95% CI accelerate Adiposity baseline Biomarker blood glucose blood lipid blood pressure body composition carried changes changes in cholesterol DBP deteriorate diastolic evaluate Fat mass Follow-up follow-up study follow-up time group HDL-C Health LDL-C linear lipoprotein cholesterol longitudinal low-density menopausal metabolic metabolic syndrome modulate participant physical physical activity Poisson Questionnaires Result Risk factors SBP serum timepoints triglycerides variables Waist circumference was used WHR women [DOI] 10.1038/s41366-021-01022-x PMC 바로가기 [Article Type] Article
Angiotensin‐Converting Enzyme 2 (SARS‐CoV‐2 receptor) expression in human skeletal muscle인간 골격근에서의 안지오텐신 분비 효소 2 (SARS -COV -2 수용체) 발현Original Article Published on 2021-10-042022-09-01 Journal: Scandinavian Journal of Medicine & Science in Spor [Category] MERS, SARS, 진단, [키워드] ACE2 ACE2 expression ACE2 protein Adiposity age analyzed angiotensin association biopsies biopsy body composition body fat cardiorespiratory cardiorespiratory fitness collected COVID‐19 determine determined by DXA enzyme exercise explained Express expression fat Interaction lean mass leg legs low fat men men and women Multiple Multiple regression analysis obesity positive Predictive Predictive value Previous studies previous study protein expression receptor regression analysis SARS‐CoV‐2 Sex difference sex differences sexual dimorphism Skeletal muscle slope subject Variability variance vastus lateralis vastus lateralis muscle VO2max was determined was reduced weight western blot women [DOI] 10.1111/sms.14061 PMC 바로가기 [Article Type] Original Article